Working Group
WG2 — Characterising and controlling biochemical interactions
WG2 disseminates methods to characterise, monitor and acutely control molecular interactions in cells, tissues and organisms.
Remit
Understanding biological mechanisms requires tools to characterise biochemical interactions and control them in space and time. WG2 connects chemists, optogenetic tool developers, biologists and technology providers to adapt these approaches across nematode systems.
Core technologies
OptogeneticsBiosensorsProteomicsTurboIDGenetic code expansionAuxin-induced degradation
Main activities
- Workshop on chemical and optical control
- Hands-on training in molecular perturbation methods
- Technology exchange with tool developers
- Collaborative protocol documentation
Expected outputs
- Workshop report
- Training material
- Technology Quarterly contributions
- White paper on transferable perturbation tools